Elan Barenholtz, Ph.D.

Associate Professor

  • Boca Raton FL UNITED STATES
  • Department of Psychology

Elan Barenholtz uses behavioral and embedded computational approaches to study the brain and behavior.

Contact

Multimedia

Social

Biography

Elan Barenholtz uses behavioral and embedded computational approaches (i.e. neural networks running in robots) to study the brain and behavior with the goal of developing a broad theoretical framework of neural function.

Areas of Expertise

Embedded Computational Neural Models
Perception and Learning
Deep Learning

Education

Rutgers University

Ph.D.

Cognitive Science

2004

Affiliations

  • Machine Perception and Cognitive Robotics (MPCR) Laboratory : Co-Director
  • FAU’s Brain Institute (I-BRAIN) : Member
  • NSF Panel : Reviewer
  • Frontiers in Psychology : Editorial Board Member

Selected Media Appearances

FAU Awarded $2.4M NSF Grant to Train Data Scientist

Boca Raton Tribune  online

2020-09-10

The project team includes Janet Robishaw, Ph.D., senior associate dean for research and chair, Department of Biomedical Science in FAU’s Schmidt College of Medicine, and an expert on genomic analysis; Ruth Tappen, Ed.D., Christine E. Lynn Eminent Scholar and Professor, FAU’s Christine E. Lynn College of Nursing, and an expert on nursing management and memory disorders; Taghi Khoshgoftaar, Ph.D., Motorola Professor in the Department of Computer and Electrical Engineering and Computer Science, and an expert on medical applications of big data analytics; Elan Barenholtz, Ph.D., an associate professor of psychology and more.

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Could robots be psychology's new lab rats?

Science Magazine  

2019-10-07

Sending a mouse through a maze can tell you a lot about how its little brain learns. But what if you could change the size and structure of its brain at will to study what makes different behaviors possible? That’s what Elan Barenholtz and William Hahn are proposing. The cognitive psychologist and computer scientist, both at Florida Atlantic University in Boca Raton, are running versions of classic psychology experiments on robots equipped with artificial intelligence. Their laptop-size robotic rovers can move and sense the environment through a camera. And they’re guided by computers running neural networks–models that bear some resemblance to the human brain...

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FAU Robo-Pup Named Astro Described As ‘First Of Its Kind In The World’

CBS Miami  

2019-09-25

“Just like a newborn baby learns how to speak and learns how to read your emotions, Astro has to learn that,” explains Elan Barenholtz, an associate professor in the FAU Department of Psychology. “So this new kind of artificual intelligence depends on a simulation of brain that’s actually living inside Astro.”...

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Selected Articles

Deep Learning Investigation of Mass Spectrometry Analysis from Melanoma Samples

IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)

EN Stark, JA Covington, S Agbroko, C Peng, WE Hahn, E Barenholtz

2019

Deep learning has yet to be widely applied in the field of chemical gas sensing, in part due to the nature of this data. Many applications of chemical gas sensing suffer from a limited number of samples of high dimensional data. In this study, a novel data approach is introduced to address these issues and is applied to a dataset from mass spectrometry (MS) for melanoma detection. Samples were taken from 32 patients presenting with a dermatological mole. Various data analyses were performed. Traditional analysis such as primary component analysis (PCA), linear discriminant analysis (LDA), and a perceptron were used. In addition, a 1-hidden layer, fully connected neural network (also known as a multilayer perceptron) and a deeper 5-hidden layer, fully connected neural network was trained to classify inputs as deriving from a melanoma or non-melanoma mole. We segmented each sample and trained the network to assign a probabilistic output interpreted as “confidence in melanoma” to each segment. Traditional inference testing on these confidence measures found highly significant differences in the outputs of the multilayer perceptrons between melanoma versus non-melanoma samples. This provides a statistically grounded approach to deep learning-based classification of small amounts of high dimensional data, given the ability to segment the samples into a sufficient number of inputs for model training.

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Self-Organizing Map Methodology for Sorting Differential Expression Data of MMP-9 Inhibition

bioRxiv

RS Clair, M Teti, A Knapinska, G Fields, W Hahn, E Barenholtz

2019

An unsupervised machine-learning model, based on a self-organizing map (SOM), was employed to extract suggested target genes from DESeq2 differential expression analysis data. Such methodology was tested on matrixmetalloproteinase 9 (MMP9) inhibitors. The model generated information on several novel gene hits that may be regulated by MMP-9, suggesting the self-organizing map method may serve as a useful analytic tool in degradomics research for further differential expression data analysis. Original data was generated from a previous study, which consisted of quantitative measures in changes of levels of gene expression from 32,000 genes in four different conditions of stimulated T-cells treated with an MMP-9 inhibitor. Since intracellular target of MMP-9 are not yet well characterized, the functional enrichment analysis program, WebGestalt, was used for validation of the SOM identified regulated genes. The proposed data analysis method indicated MMP-99s prominent role in biological regulatory and metabolic processes as major categories of regulation of the predicted genes. Both fields suggest extensive intracellular targets for MMP-9-triggered regulation, which are new interests in MMP-9 research. The methodology presented here is useful for similar knowledge and discovery from quantitative datasets and a proposed extension of DESeq2 or similar data analysis.

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Medicine Has Gone to the Dogs: Deep Learning and Robotic Olfaction to Mimic Working Dogs

IEEE Technology and Society Magazine

E Stark, S Hoover, A DeCesare, E Barenholtz

2018

Canines and humans have coexisted for millennia, to our mutual benefit. Our estimated 35 000+ year history of coevolution, including selective breeding, has lead to the development of intimate forms of cooperation, perhaps unparalleled among mammalian species [26]. In addition to providing companionship, dogs can perform critical roles for humans, such as mental health support and aid for the disabled. Recent years have seen growth in the deployment of service dogs, which are trained to perform a specialized task to mitigate a disability, providing higher quality care, increased independence, and peace of mind for those with life-threatening illnesses.

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